Thermoresponsive Microtextured Culture Surfaces Facilitate Fabrication of Capillary Networks
2007; Volume: 19; Issue: 21 Linguagem: Inglês
10.1002/adma.200700988
ISSN1521-4095
AutoresYukiko Tsuda, Masayuki Yamato, Akihiko Kikuchi, Masahiro Watanabe, Guoping Chen, Y. Takahashi, Teruo Okano,
Tópico(s)Hydrogels: synthesis, properties, applications
ResumoAdvanced MaterialsVolume 19, Issue 21 p. 3633-3636 Communication Thermoresponsive Microtextured Culture Surfaces Facilitate Fabrication of Capillary Networks† Y. Tsuda, Y. Tsuda Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, 8-1 Kawadacho, Shinjuku, Tokyo 162-8666 (Japan) Graduate School of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8571 (Japan) Biomaterials Center, National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044 (Japan)Search for more papers by this authorM. Yamato, M. Yamato Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, 8-1 Kawadacho, Shinjuku, Tokyo 162-8666 (Japan)Search for more papers by this authorA. Kikuchi, A. Kikuchi Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, 8-1 Kawadacho, Shinjuku, Tokyo 162-8666 (Japan) Present address: Department of Materials Science and Technology, Tokyo University of Science, 2641 Yamazaki, Noda-shi, Chiba 278-8510, JapanSearch for more papers by this authorM. Watanabe, M. Watanabe Research & Development Center, Dai Nippon Printing Co., Ltd., 250-1 Wakashiba, Kashiwa, Chiba 277-0871 (Japan)Search for more papers by this authorG. Chen, G. Chen Graduate School of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8571 (Japan) Biomaterials Center, National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044 (Japan)Search for more papers by this authorY. Takahashi, Y. Takahashi Research & Development Center, Dai Nippon Printing Co., Ltd., 250-1 Wakashiba, Kashiwa, Chiba 277-0871 (Japan)Search for more papers by this authorT. Okano, T. Okano [email protected] Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, 8-1 Kawadacho, Shinjuku, Tokyo 162-8666 (Japan)Search for more papers by this author Y. Tsuda, Y. Tsuda Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, 8-1 Kawadacho, Shinjuku, Tokyo 162-8666 (Japan) Graduate School of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8571 (Japan) Biomaterials Center, National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044 (Japan)Search for more papers by this authorM. Yamato, M. Yamato Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, 8-1 Kawadacho, Shinjuku, Tokyo 162-8666 (Japan)Search for more papers by this authorA. Kikuchi, A. Kikuchi Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, 8-1 Kawadacho, Shinjuku, Tokyo 162-8666 (Japan) Present address: Department of Materials Science and Technology, Tokyo University of Science, 2641 Yamazaki, Noda-shi, Chiba 278-8510, JapanSearch for more papers by this authorM. Watanabe, M. Watanabe Research & Development Center, Dai Nippon Printing Co., Ltd., 250-1 Wakashiba, Kashiwa, Chiba 277-0871 (Japan)Search for more papers by this authorG. Chen, G. Chen Graduate School of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8571 (Japan) Biomaterials Center, National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044 (Japan)Search for more papers by this authorY. Takahashi, Y. Takahashi Research & Development Center, Dai Nippon Printing Co., Ltd., 250-1 Wakashiba, Kashiwa, Chiba 277-0871 (Japan)Search for more papers by this authorT. Okano, T. Okano [email protected] Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, 8-1 Kawadacho, Shinjuku, Tokyo 162-8666 (Japan)Search for more papers by this author First published: 05 October 2007 https://doi.org/10.1002/adma.200700988Citations: 25 † The authors appreciate the useful comments and technical criticism from J. Yang (Tokyo Women's Medical University) and Dr. B. C. Isenberg (Boston University). The authors thank Y. Shigematsu (Tokyo Women's Medical University) and Prof. M. Wada (Nara Women's University) for their technical assistance with confocal laser scanning microscopy. The authors also acknowledge T. Tonegawa (National Institute for Materials Science, Japan) for his technical assistance with the SEM observations. The present research was supported by Formation of Innovation Center for Fusion of Advanced Technologies in the Special Coordination Funds for Promoting Science and Technology from the Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan. Y.T. acknowledges support from a Japan Society for Promotion of Science Research Fellowship (Project No. 17-7231). AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract A novel cell culture surface is developed that induces the tubular formation of endothelial cells and facilitates the intact harvesting of fabricated capillary-like structures by utilizing a thermoresponsive polymer, poly(N-isopropylacrylamide). The tubular cell networks, such as the one shown in the figure, may be applicable for the fabrication of 3D vascularized tissue grafts. Citing Literature Volume19, Issue21November, 2007Pages 3633-3636 RelatedInformation
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