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Vaccinia Virus Infection in Monkeys, Brazilian Amazon

2010; Centers for Disease Control and Prevention; Volume: 16; Issue: 6 Linguagem: Inglês

10.3201/eid1606.091187

1080-6059

Jônatas Santos Abrahão, André T. Fernandes, Larissa Soares Lima, Rafael K. Campos, Maria Isabel Maldonado Coelho Guedes, Marcela Menezes Gomes Cota, Felipe Lopes de Assis, Iara A. Borges, Milton F. Souza-Júnior, Zélia Inês Portela Lobato, Cláudio Antônio Bonjardim, Paulo César Peregrino Ferreira, Giliane S. Trindade, Geessien Kroon Erna,

Virus-based gene therapy research

To detect orthopoxvirus in the Brazilian Amazon, we conducted a serosurvey of 344 wild animals. Neutralizing antibodies against orthopoxvirus were detected by plaque-reduction neutralizing tests in 84 serum samples. Amplicons from 6 monkey samples were sequenced. These amplicons identified vaccinia virus genetically similar to strains from bovine vaccinia outbreaks in Brazil.