Fluorescent peptide probes for in vivo diagnostic imaging
2004; Wiley; Volume: 76; Issue: 5 Linguagem: Inglês
10.1002/bip.20139
ISSN1097-0282
Autores Tópico(s)Click Chemistry and Applications
ResumoAbstract Recently, many novel peptide‐based near‐infrared (NIR) fluorescent molecular probes have been developed for in vivo biomedical imaging. To report specific information of biological targets, the probes were individually designed according to the unique property or functions of their targets. These peptide‐based probes can be classified into targeting, crosslinking, and enzyme‐activatable probes. Several of them have been tested in various in vitro and in vivo models, and the obtained imaging information has been applied to disease detection, medical diagnosis, and drug evaluations. © 2004 Wiley Periodicals, Inc. Biopolymers (Pept Sci), 2004
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