Portal de Periódicos da CAPES

Recent advances in stereoselective glycosylation through intramolecular aglycon delivery

2010; Royal Society of Chemistry; Volume: 8; Issue: 16 Linguagem: Inglês

10.1039/c004281a

1477-0539

Akihiro Ishiwata, Yong Joo Lee, Yukishige Ito,

Chemical Synthesis and Analysis

Methodology toward the stereoselective 1,2-cis glycoside linkage using intramolecular aglycon delivery (IAD) has been extensively developed. In the last two decades, progress has been made using various mixed acetal linkages and a number of glycosyl donor moieties to develop novel IAD strategies, mainly based on formation of acetal linkages. This account summarizes the newest naphthylmethyl (NAP) ether-mediated IAD as well as all the types of mediations for stereospecific construction of various 1,2-cis linkages, not only for beta-mannopyranoside, but also for other linkages almost without exception, including beta-L-rhamnoside.