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Arene cis-dihydrodiol formation: from biology to application

2005; Royal Society of Chemistry; Volume: 4; Issue: 2 Linguagem: Inglês

10.1039/b513226f

1477-0539

Derek R. Boyd, Timothy D. H. Bugg,

Oxidative Organic Chemistry Reactions

The range of available arene dihydroxylating dioxygenase enzymes, their structure and mechanism, and recent examples of the application of arene cis-dihydrodiol bioproducts as chiral precursors in the synthesis of natural and unnatural products and chiral ligands are discussed.