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Prevention of Pneumocystis carinii Pneumonia Relapse by Aerosolised Pentamidine, 60 mg Biweekly, Using an Acorn System 22 Nebuliser

1990; Informa; Volume: 22; Issue: 5 Linguagem: Inglês

10.3109/00365549009027092

1651-1980

Birgitte Nybo Jensen, Thyge L. Nielsen, B Lerche, Tom Hartvig Jensen, Vibeke Backer, Peter M. H. Heegaard, Jens Nielsen, Peter Skinhøj,

Tuberculosis Research and Epidemiology

The effectiveness of biweekly administration of 60 mg aerosolised pentamidine (AP) as secondary prophylaxis against relapse of Pneumocystis carinii pneumonia (PCP) was investigated in 45 male AIDS patients. The nebuliser used was an Acorn System 22. In total the patients received AP for a mean period of 13.8 months (3.4–28.8). Six episodes of recurrent PCP were recorded. Relapse per full year of treatment on AP was 12%.