Humoral and Cellular Response in Humans After Immunization with Influenza Vaccine
1973; American Society for Microbiology; Volume: 7; Issue: 4 Linguagem: Inglês
10.1128/iai.7.4.594-596.1973
ISSN1098-5522
AutoresFrederick L. Ruben, George Gee Jackson, Samuel P. Gotoff,
Tópico(s)Immune Cell Function and Interaction
ResumoThe peripheral blood lymphocyte response and hemagglutination inhibition antibody titers were measured in nine adults before and after immunization with a killed split influenza virus vaccine. Cord blood lymphocytes were tested with the influenza antigen to exclude a nonspecific mitogenic effect. All of the subjects demonstrated preexisting antibody titers and antigen recognition by lymphocytes prior to immunization. The in vitro lymphocyte response after vaccination parallels the humoral antibody response to influenza antigen.
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