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BIBTEX RIS

Rectal diazepam in the treatment of absence status: a pharmacodynamic study

1981; BMJ; Volume: 44; Issue: 10 Linguagem: Inglês

10.1136/jnnp.44.10.914

ISSN

1468-330X

Autores

N. Milligan, S. Dhillon, A. Richens, J Oxley,

Tópico(s)

Plant-based Medicinal Research

Resumo

Rectal administration of diazepam is highly effective in terminating absence status as judged by reduction of spike-wave activity in the EEG. Pharmacokinetic studies indicate that diazepam can have antiepileptic properties at serum levels well below those previously reported as being necessary to achieve a therapeutic effect.

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