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A Detection System Based on Giant Magnetoresistive Sensors and High‐Moment Magnetic Nanoparticles Demonstrates Zeptomole Sensitivity: Potential for Personalized Medicine

2009; Wiley; Volume: 48; Issue: 15 Linguagem: Inglês

10.1002/anie.200806266

1521-3773

Balasubramanian Srinivasan, Yuanpeng Li, Ying Jing, Yun-Hao Xu, Xiaofeng Yao, Chengguo Xing, Jian‐Ping Wang,

Advanced Biosensing Techniques and Applications

Zeptomole detector: A highly sensitive giant-magnetoresistive chip and FeCo nanoparticles can be used to linearly detect 600-4500 copies of streptavidin. Under unoptimized conditions, this system also detects human IL-6 with a sensitivity 13-times higher than that of standard ELISA techniques.