Artigo Revisado por pares

Gm Allotyping to Determine the Origin of the Anti‐D Causing Hemolytic Anemia in a Kidney Transplant Recipient

1987; Wiley; Volume: 52; Issue: 3 Linguagem: Inglês

10.1111/j.1423-0410.1987.tb03033.x

ISSN

1423-0410

Autores

Jane L. Swanson, Elizabeth S. Sebring, Robert M. Sastamoinen, M. Chopek,

Tópico(s)

Erythrocyte Function and Pathophysiology

Resumo

Abstract. Anti‐D causing mild hemolytic anemia was found in the serum and on the red cells of a D‐positive patient who had received a kidney transplant from his D‐negative mother. Anti‐D had been detected in the donor's serum before transplantation. Gm allotyping of the patient's serum, donor's serum, donor's anti‐D, and the unex pected anti‐D in the posttransplantation serum showed the antibody to be of maternal origin. The patient was Gm(fb), the donor Gm(agfb), the maternal anti‐D Gm (afb), and the anti‐D in the posttransplantation serum was Gm(a).

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