Portal de Periódicos da CAPES

Pharmacological and Cultural Considerations in Alcohol Treatment Clinical Trials: Issues in Clinical Research Related to Race and Ethnicity

2003; Wiley; Volume: 27; Issue: 8 Linguagem: Inglês

10.1097/01.alc.0000080341.10023.2f

1530-0277

Robert E. Taylor,

Alcohol Consumption and Health Effects

Alcoholism: Clinical and Experimental ResearchVolume 27, Issue 8 p. 1345-1348 Pharmacological and Cultural Considerations in Alcohol Treatment Clinical Trials: Issues in Clinical Research Related to Race and Ethnicity Robert E. Taylor, Corresponding Author Robert E. Taylor Collaborative Alcohol Research Center, Howard University, Washington, DC.Robert E. Taylor, M.D., Ph.D., Department of Pharmacology, Howard University College of Medicine, 520 W. Street, N.W., #3408, Washington, DC 20059; Fax: 202-806-4453; E-mail: [email protected]Search for more papers by this author Robert E. Taylor, Corresponding Author Robert E. Taylor Collaborative Alcohol Research Center, Howard University, Washington, DC.Robert E. Taylor, M.D., Ph.D., Department of Pharmacology, Howard University College of Medicine, 520 W. Street, N.W., #3408, Washington, DC 20059; Fax: 202-806-4453; E-mail: [email protected]Search for more papers by this author First published: 03 May 2006 https://doi.org/10.1097/01.ALC.0000080341.10023.2FCitations: 11 This work was supported by National Institute on Alcohol Abuse and Alcoholism Grants U24-11888, RO-1-12553, R-21-13531, and N01 AA-1016 and by support from the National Center for Minority Health and Health Disparities, National Institutes of Health. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES Ahluwalia JS, Richter K, Mayo MS, Ahluwalia HK, Choi WS, Schmelzle KH, Resnicow K (2002) African American smokers interested and eligible for a smoking cessation clinical trial: predictors of not returning for randomization Ann Epidemiol 3: 206–212. Arranz MJ, Munro J, Birkett J, Bolonna A, Mancama D, Sodhi M, Lesch KP, Meyer JFW, Sham P, Collier DA, Murray RM, Kerwin RW (2000) Pharmacogenetic prediction of clozapine response Lancet 355: 1615–1616. Bonham VL (2002) Ethical, Legal, and Social Implications: A Community View Presentation at Symposium on Genomic Medicine, National Medical Association. National Human Genome Institute, Bethesda , Maryland , June 24–25. Burchard EG, Ziv E, Coyle N, Gomez SL, Tang H, Karter AJ, Mountain JL, Perez-Stable EJ, Sheppard D, Risch N (2003) The importance of race and ethnic background in biomedical research and clinical practice N Engl J Med 348: 1170–1175. Cha AE (2003) Race plays role in new drug trials. Washington Post . July 28, 2003, A1. Cooper RS, Kaufman JS, Ward R (2003) Race and genomics N Engl J Med 348: 1166–1170. Exner DV, Dries DL, Domanski MJ, Cohn JN (2001) Lesser response to angiotensin-converting-enzyme inhibitor therapy in blacks as compared with white patients with left ventricular dysfunction N Engl J Med 344: 1351–1357. Foster MW, Sharp RR (2002) Race, ethnicity, and genomics: social classifications as proxies of biological heterogeneity Genome Res 12: 844–850. Gifford AL, Cunningham WE, Heslin KC, Andersen RM, Nakazono T, Lieu DK, Shapiro MF, Bozzette SA (2002) Participation in research and access to experimental treatments by HIV-infected patients N Engl J Med 346: 1373–1382. Guttmacher AE, Collins FS (2002) Genomic medicine: a primer N Engl J Med 347: 1512–1520. Hazuda HP, Comeaux PJ, Stern MP, Haffner SM, Eifler CW, Rosenthal (1996) A comparison of three indicators for identifying Mexican Americans in epidemiologic research Am J Epidemiol 123: 96–110. Humphreys K, Weisner C (2000) Use of exclusion criteria in selecting research subjects and its effect on the generalizability of alcohol treatment outcome studies Am J Psychiatry 157: 588–594. Jackson FLC (1992) Race and ethnicity as biological constructs Ethn Dis 2: 120–125. Jackson FLC (1993) The bioanthropological context of disease Am J Kidney Dis 21: 10–14. Janson SL, Alioto ME, Boushey HA (2001) Attrition and retention of ethically diverse subjects in a multicenter randomized controlled research trial Control Clin Trials 22: 236S–243S. Kauffman J, Cooper RS (1995) In search of the hypothesis Public Health Rep 110: 662–666. King TE (2002) Racial disparities in clinical trials N Engl J Med 346: 1400–1402. Kressin NR, Meterko M, Wilson N (2000) Racial disparities in participation in biomedical research J Natl Med Assoc 92: 62–68. Mabunda-Temple G (1998) Recruitment of African Americans in AIDS clinical trials: some recommended strategies J Assoc Black Nurs Faculty 3: 61–64. Odocha OH (2000) Race and racialism in scientific research and publications in the Journal of the National Medical Association J Natl Med Assoc 92: 96–98. Phimister EG (2003) Medicine and the racial divide N Engl J Med 348: 1081–1082. Pickar D, Rubinow K (2001) Pharmacogenomics of psychiatric disorders Trends Pharmacol Sci 22: 75–83. Risch N, Burchard E, Ziv E, Tang H (2002) Categorization of humans in biomedical research: genes, race and disease Genome Biol 3: 1–12. Rubin RR, Fujimoto WY, Marrero DG, Brenneman T, Charleston JB, Edelstein SL, Fisher EB, Jordan R, Knowler WC, Lichterman LC, Prince M, Rowe PM The DPP Research Group (2002) The diabetes prevention program: recruitment methods and results Control Clin Trials 23: 157–171. Satel S (2002) I am a racially profiling doctor. New York Times 6: 56. Schwartz RS (2001) Racial profiling in medical research N Engl J Med 344: 1392–1393. Shavers-Hornaday VL, Lynch CF, Burnmeister LF, Torner JC (1997) Why are African Americans under-represented in medical research studies? Impediments to participation Ethn Health 2: 31–45. Sorkness CA, Ford JG, Lemanske RF (2001) Recruitment strategies in the asthma clinical research network Control Clin Trials 22: 222S–235S. Splawski I, Timothy KW, Tateyama M, Clancy CE, Malhotra A, Beggs AH, Cappuccio FP, Sagnella GA, Kass RS, Keating MT (2002) Variant of SCN5A sodium channel implicated in risk of cardiac arrhythmia Science 297: 1333–1336. Wood AJ (2001) Racial differences in the response to drugs—pointers to genetic differences N Engl J Med 344: 1393–1395. Woodcock RW, McGrew KS, Werder JK (1994) Woodcock-McGrew-Werder Mini-Battery of Achievement. Riverside Publishing, Itasca , IL . Yancy CW, Fowler MB, Colucci WS, Gilbert EM, Bristow MR, Cohn JN, Lukas MA, Young ST, Packer M (2001) Race and the response to adrenergic blockade with carvedilol in patients with chronic heart failure N Engl J Med 344: 1358–1365. Citing Literature Volume27, Issue8August 2003Pages 1345-1348 ReferencesRelatedInformation