Respiratory Muscles: The Vital Pump
1980; Elsevier BV; Volume: 78; Issue: 5 Linguagem: Inglês
10.1378/chest.78.5.753
ISSN1931-3543
Autores Tópico(s)Chronic Obstructive Pulmonary Disease (COPD) Research
ResumoIn recent years, the old hypothesis that one could load the respiratory muscles to the point where they become fatigued and could no longer continue the task of ventilating to maintain a normal PaCO2, has been confirmed. 1 Roussos C Macklem PT Diaphragmatic fatigue in man. J Appl Physiol. 1977; 43: 189-197 Crossref PubMed Scopus (314) Google Scholar , 2 Roussos C Finley M Gross D Macklem PT Fatigue of inspiratory muscles and their synergic behaviour. J Appl Physiol. 1979; 46: 897-904 Crossref PubMed Scopus (152) Google Scholar It is easy to produce inspiratory muscle fatigue in normal volunteers and in experimental animals, to study the factors which influence its development, and to observe the clinical manifestations of fatigue in order that we may diagnose it in patients.
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