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BIBTEX RIS

Estimated number of cases, regional distribution and survival of patients diagnosed with acute myeloid leukemia between 1996 and 2000 in Rio Grande do Sul, Brazil

2007; Taylor & Francis; Volume: 48; Issue: 12 Linguagem: Inglês

10.1080/10428190701713622

1042-8194

Marcelo Capra, Líbia Vilella, Waldir Veiga Pereira, Virgínia Maria Cóser, Mário Fernandes, Marco Antônio Schilling, Denise Ramos de Almeida, Mauro Gross, Márcia Leite, Tânia Hellwig, Gilca Natchigal, Alice Zelmanowicz, Giorgio Adriano Paskulin, Jorge Neumann, Lúcia Mariano da Rocha Silla,

Hemoglobinopathies and Related Disorders

Rio Grande do Sul (RS), in South Brazil, with about 10 million inhabitants, is known for its agricultural activities and consequent increased human exposure to toxic agents. Patients with de novo acute myeloid leukemia (AML) were included based on information retrieved from all referral hospitals in RS between 1996 and 2000. A total of 532 patients were registered. Median age at diagnosis was 42 years. The estimated annual incidence was 1.11 cases/100 000 inhabitants/year. There was an estimated incidence of 0.5 – 1 case per 100 000 inhabitants up to the age of 45 years, and of 3.5 cases per 100 000 inhabitants aged 70 years and older, with no geographical clusters. The mean 5-year survival rate was 17% for all cases. There was an increased number of M3 cases, as already described for individuals of Latin-American and the mortality rate was similar to that described in the literature.