ACUTE RESPIRATORY DISTRESS SYNDROME IN SCRUB TYPHUS
2007; American Society of Tropical Medicine and Hygiene; Volume: 76; Issue: 6 Linguagem: Inglês
10.4269/ajtmh.2007.76.1148
ISSN1476-1645
AutoresChin‐Chou Wang, Shih‐Feng Liu, Jien-Wei Liu, Yu‐Hsiu Chung, Mao‐Chang Su, Meng‐Chih Lin,
Tópico(s)Vector-borne infectious diseases
ResumoScrub typhus is a mite-borne infectious disease caused by Orientia tsutsugamushi. Acute respiratory distress syndrome (ARDS) is a serious complication of scrub typhus. This study retrospectively reviewed the medical records of 72 patients diagnosed with scrub typhus from January 1998 to August 2006 in Kaohsiung Chang Gung Memorial Hospital in Taiwan. Eight of 72 scrub typhus patients with ARDS were included in the study; the other patients without ARDS were used as controls. The mortality rate for the scrub typhus patients with ARDS was 25%. The eight patients seldom had underlying diseases. Initial presentations of dyspnea and cough, white blood cell count, hematocrit, total bilirubin, and delayed used of appropriate antibiotics use were significant predictors of ARDS. Multivariate analysis showed that albumin, prothrombin time, and delayed use of appropriate antibiotics were independent predictors of ARDS. Identification of these relative risk factors may help clinicians evaluate clinical cases of scrub typhus with ARDS.
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