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Phytochemical analysis and antimicrobial activity of Scoparia dulcis and Nymphaea lotus.

2009; International Network for Scientific Information Publication; Volume: 3; Issue: 4 Linguagem: Inglês

2309-8414

J. Yisa,

Plant Toxicity and Pharmacological Properties

Two medicinal plants, Scoparia dulcis (Scrophulariaceae) and Nymphaea lotus (Nympaeaceae) were studied to verify their medicinal claims by the Nupes in Nigeria. The crude aqueous and ethanolic extracts of the medicinal plants were tested against Stapylococcus aureus, Microsporum canis, Candida albicans, Salmonella typhi, Streptococcus species, Escherichia coli and Proteus vulgaris. Ethanolic extracts of Scoparia dulcis and Nymphaea lotus produced greater zones of inhibitions on Staphylococcus aureus and Streptococcus species while aqueous extracts produced zones of inhibition on Staphylococcus aureus from both plants. The ethanolic extracts of Scoparia dulcis produced zones of inhibition on Microsporum canis and Candida albicans while ethanolic extract of Nymphaea lotus produced zones of inhibition on Candida albicans. Escherichia coli, Samonella typhi and Proteus vulgaris were the most resistant. Bioactive agents like Saponins, glycoside and carbohydrate were detected in Scoparia dulcis, while saponins, tannins and alkaloids were found in Nymphaea lotus. The interest in the scientific investigation of these medicinal plants from Nupe land, Niigeria is based on the claims of their effective use for the treatment of many diseases. Therefore, research into the effects of these local medicinal plants is expected to enhance the use of these plants against diseases caused by the test pathogens. However, most of these plants used in folk medicine have not been screened for their antimicrobial activity. Therefore, basic phytochemical investigation of these extracts for their major phytoconstituents is also vital. In the present study, the ethanolic and aqueous extracts from Scoparia dulcis and Nymphaea lotus plants were screened for phytochemical constituents and antimicrobial activity against Escherichia coli, Staphylococcus aureus, Streptococcus species, Candida albicans, Microsporum canis, Proteus Vulgaris and Salmonella typhi.