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Familial Hypercholesterolemia

2014; Deutscher Ärzte-Verlag; Linguagem: Inglês

10.3238/arztebl.2014.0523

1866-0452

Gerald Klose, Ulrich Laufs, Winfried März, E. Windler,

Diabetes, Cardiovascular Risks, and Lipoproteins

Familial hypercholesterolemia (FH) is a congenital disorder of lipid metabolism characterized by a marked elevation of the plasma concentration of LDL (low-density lipoprotein) cholesterol beginning in childhood and by the early onset of coronary heart disease. It is among the commonest genetic disorders, with an estimated prevalence in Germany of at least 1 per 500 persons.