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The Biology of Coronaviruses

1983; Microbiology Society; Volume: 64; Issue: 4 Linguagem: Inglês

10.1099/0022-1317-64-4-761

1465-2099

Stuart G. Siddell, H. Wege, Volker ter Meulen,

SARS-CoV-2 and COVID-19 Research

Introduction The Coronaviridae is a monogeneric family comprising 11 viruses which infect vertebrates. Members of the group are responsible for diseases of clinical and economic importance, in particular respiratory and gastrointestinal disorders (Table 1). The group was originally recognized on the basis of a characteristic virion morphology (Tyrrell et al., 1968), but can now be defined by biological and molecular criteria. Various aspects of coronavirus biology have been dealt with in recent reviews (Robb & Bond, 1979; Siddell et al., 1982; Wege et al., 1982).