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BIBTEX RIS

The novel angiogenic cytokine secretoneurin promotes angiogenesis, arteriogenesis and vasculogenesis in the mouse hind-limb ischemia model

2008; BioMed Central; Volume: 8; Issue: S1 Linguagem: Inglês

10.1186/1471-2210-8-s1-a38

ISSN

1471-2210

Autores

Wilfried Schgoer, Margot Egger, Arno Beer, Markus Theurl, Johannes Jeschke, Ivan Tancevski, Kathrin Eller, Andreas Ritsch, Hildegunde Piza‐Katzer, Josef R. Patsch, Peter Schratzberger, Reiner Fischer‐Colbrie, Rudolf Kirchmair,

Tópico(s)

Chemokine receptors and signaling

Resumo

Secretoneurin (SN) represents a sensory, inflammatory neuropeptide which was recently demonstrated to act as an angiogenic and vasculogenic cytokine in vitro and in vivo. The present study was conducted to test the hypothesis that SN may be implicated in reparative angiogenesis. Furthermore, we challenged the healing potential of SN applied as a newly generated SN gene therapy vector in the setting of limb ischemia.

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