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The feasibility of HIV vaccine efficacy trials among Russian injection drug users

2007; Elsevier BV; Volume: 25; Issue: 41 Linguagem: Inglês

10.1016/j.vaccine.2007.07.028

1873-2518

Chris Beyrer, Stefan Baral, Алла Вадимовна Шаболтас, Elena Dukhovlinova, Alexey Masharsky, Sergei V. Verevochkin, Carl A. Latkin, Robert Heimer, Irving Hoffman, Andrei P. Kozlov,

HIV Research and Treatment

IDU exposure remains a primary driver of the Russian HIV epidemic, and recent incidence data provide little evidence that this epidemic is slowing. While there are multiple important challenges that need to be further explored before starting vaccine trials, most importantly access to evidence-based drug treatment services for trial participants, the current context of high HIV incidence and low genetic diversity of HIV strains, suggests the need for intensified prevention strategies and supports the feasibility of mounting efficacy trials of HIV vaccines among IDUs in the Russian Federation.