Portal de Periódicos da CAPES

Circadian variations in 32P uptake of a DMBA-induced mammary tumour and Walker carcinosarcoma in rats

1976; Springer Nature; Volume: 33; Issue: 6 Linguagem: Inglês

10.1038/bjc.1976.102

1532-1827

Ulla Møller, J. Bojsen,

Digestive system and related health

The 32P uptake in a mammary tumour induced by DMBA and in the Walker 256 carcinosarcoma was measured by external GM -tubes. The uptake was significantly higher than in the skin. During exposure to a synchronized light regime a circadian variation was present in the 32P uptake of the hormone-dependent DMBA-induced tumour. The maximal 32P uptake was in the dark period, in which the highest temperature in the tumour has also been found (Møoller and Bojsen, 1975). In the hormone-independent Walker 256 carcinosarcoma there was no periodicity in 32P uptake. No variation in 32P uptake was registered in the skin of normal controls or in tumour-bearing rats.