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Harzianic Acid, an Antifungal and Plant Growth Promoting Metabolite from Trichoderma harzianum

2009; American Chemical Society; Volume: 72; Issue: 11 Linguagem: Inglês

10.1021/np900548p

1520-6025

Francesco Vinale, Gavin R. Flematti, K. Sivasithamparam, Matteo Lorito, Roberta Marra, Brian W. Skelton, Emilio L. Ghisalberti,

Essential Oils and Antimicrobial Activity

A Trichoderma harzianum strain, isolated from composted hardwood bark in Western Australia, was found to produce a metabolite with antifungal and plant growth promoting activity. The structure and absolute configuration of the fungal compound, harzianic acid (1), were determined by X-ray diffraction studies. Harzianic acid showed antibiotic activity against Pythium irregulare, Sclerotinia sclerotiorum, and Rhizoctonia solani. A plant growth promotion effect was observed at low concentrations of 1.