Artigo Revisado por pares

Microbial hydroxylations of further octalin derivatives

1991; Elsevier BV; Volume: 32; Issue: 17 Linguagem: Inglês

10.1016/0040-4039(91)85019-2

ISSN

1873-3581

Autores

Jamal Ouazzani, Arséniyadis Siméon, Ramón Álvarez-Manzaneda, Ángel Rumbero, Guy Ourisson,

Tópico(s)

Microbial Metabolic Engineering and Bioproduction

Resumo

The allylic hydroxylation of octalin derivatives with Rhizopus arrhizus proceeds with high to excellent yields, even in the presence of substituents such as acetate, phosphate, free ketone or dioxolane, but not a benzyl group. One of the Me groups of a t-Bu ether can be hydroxylated.

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