Regioselective Aromatic Electrophilic Bromination with Dioxane Dibromide Under Solvent‐Free Conditions
2007; Taylor & Francis; Volume: 37; Issue: 4 Linguagem: Inglês
10.1080/00397910601055081
ISSN1532-2432
AutoresSubrata Kumar Chaudhuri, Sanchita Roy, Malay Saha, Sanjay Bhar,
Tópico(s)Oxidative Organic Chemistry Reactions
ResumoAbstract Highly regioselective ring bromination of aromatic compounds has been accomplished with high yields and good purity using dioxane dibromide (DD) under solvent‐free conditions. Notable features of this methodology include operational simplicity, rapid reactions, excellent control over the degree of bromination, and tolerance of various functional groups during the reaction. Keywords: electrophilic aromatic substitutionregioselectivity, solid‐phase synthesis Acknowledgments Financial support from the Council of Industrial and Scientific Research, New Delhi (Grant No. 01(1673)/00/EMR‐II dated 07‐12‐2000), is gratefully acknowledged. S. R. thanks the University Grants Commission, New Delhi, and M. S. thanks CSIR, New Delhi, for junior research fellowships. The authors express profound thanks to N. Dutta of the Indian Association for the Cultivation of Science for necessary assistance.
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