Family history of autoimmune diseases in psychosis
1996; Elsevier BV; Volume: 19; Issue: 1 Linguagem: Inglês
10.1016/0920-9964(95)00045-3
ISSN1573-2509
AutoresCatherine Gilvarry, Pak C. Sham, Peter B. Jones, Mary Cannon, Pádraig Wright, Shôn Lewis, Paul Bebbington, Brian Toone, Robin M. Murray,
Tópico(s)Growth Hormone and Insulin-like Growth Factors
ResumoThe mothers of 101 psychotic patients and 116 normal controls were interviewed using a semi-structured questionnaire designed to determine the presence or absence of autoimmune disorders in first degree relatives of the probands. Thyrotoxicosis and insulin-dependent diabetes mellitus were significantly more common in the relatives of the psychotic patients than in the control relatives; in particular thyrotoxicosis was more frequent in the mothers of patients (11%) than the mothers of controls (2.6%). None of the examined characteristics of the patients, including RDC-diagnosis, family history of psychosis, age at onset of psychosis and winter birth, was predictive of thyrotoxicosis- and insulin-dependent diabetes mellitus in relatives.
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