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Comparison of surgical outcomes of gastric cancer in elderly and middle-aged patients

2006; Elsevier BV; Volume: 191; Issue: 2 Linguagem: Inglês

10.1016/j.amjsurg.2005.09.001

1879-1883

Chikara Kunisaki, Hirotoshi Akiyama, Masato Nomura, Goro Matsuda, Yuichi Otsuka, Hidetaka Ono, Hiroshi Shimada,

Metastasis and carcinoma case studies

We compared clinicopathological features and results of surgery for gastric carcinoma in elderly and middle-aged patients to develop appropriate treatment for elderly patients with gastric carcinoma.Surgical results were assessed for 135 elderly patients (over 75 years old) and 665 middle-aged patients (between 45 and 65 years old) with gastric cancer.Distinct characteristics of elderly patients were male predominance; macroscopically well, or ill-defined, histologically differentiated tumors; and advanced stage disease. There was a significant difference in overall survival between the groups for early stage carcinomas but no difference in cause-specific survival. Postoperative morbidities did not differ between the curatively resected patients in the 2 groups. Moreover, deaths from other cancers or comorbid disease were frequent among the elderly.Meticulous treatment and follow-up not only for gastric carcinoma but also for other diseases would improve survival in elderly patients, particularly those with early-stage tumors.