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Comparison of the Effectiveness of Embolic Agents for Bronchial Artery Embolization: Gelfoam versus Polyvinyl Alcohol

2010; Korean Society of Radiology; Volume: 11; Issue: 5 Linguagem: Inglês

10.3348/kjr.2010.11.5.542

2005-8330

Seok Hahn, Young Jin Kim, Woocheol Kwon, Seung-Whan Cha, Won‐Yeon Lee,

Gastrointestinal Bleeding Diagnosis and Treatment

Comparison of the Effectiveness of Embolic Agents for Bronchial Artery Embolization: Gelfoam versus Polyvinyl AlcoholObjective: The purpose of this study was to compare the results of different agents for bronchial artery embolization of hemoptysis. Materials and Methods:From March 1992 to December 2006, a bronchial artery embolization was performed on 430 patients with hemoptysis.The patients were divided into three groups.Group 1 included 74 patients treated with a gelfoam particle (1×1×1 mm), while group 2 comprised of 205 patients treated with polyvinyl alcohol (PVA) at 355-500 μ m, and group 3 included 151 patients treated with PVA at 500-710 μ m.We categorized the results as technical and clinical successes, and also included the mid-term results.Retrospectively, the technical success was compared immediately after the procedure.The clinical success and mid-term results (percentage of patients who were free of hemoptysis) were compared at 1 and 12 months after the procedure, respectively.Results: Neither the technical successes (group 1; 85%, 2; 85%, 3; 90%) nor the clinical successes (group 1; 72%, 2; 74%, 3; 71%) showed a significant difference among the 3 groups (p > 0.05).However, the mid-term results (group 1; 45%, 2; 63%, 3; 62%) and mid-term results excluding the recurrence from collateral vessels in each of the groups (group 1; 1 patient, 2; 4 patients, 3; 2 patients) showed that group 1 was lower than the other two groups (p < 0.05).No significant difference was discovered for the mid-term results between groups 2 and 3.Moreover, the same results not including incidences of recurrence from collateral vessels also showed no statistical significance between the two groups (p > 0.05). Conclusion:Polyvinyl alcohol appears to be the more optimal modality compared to gelfoam particle for bronchial artery embolization in order to improve the mid-term results.The material size of PVA needs to be selected to match with the vascular diameter.