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NO RELATIONSHIP OF TESTICULAR SIZE AT ORCHIOPEXY WITH FERTILITY IN MEN WHO PREVIOUSLY HAD UNILATERAL CRYPTORCHIDISM

2001; Lippincott Williams & Wilkins; Volume: 166; Issue: 1 Linguagem: Inglês

10.1016/s0022-5347(05)66134-4

1527-3792

Peter A. Lee, Michael T. Coughlin, Mark F. Bellinger,

Sexual Differentiation and Disorders

No AccessJournal of UrologyPEDIATRIC UROLOGY1 Jul 2001NO RELATIONSHIP OF TESTICULAR SIZE AT ORCHIOPEXY WITH FERTILITY IN MEN WHO PREVIOUSLY HAD UNILATERAL CRYPTORCHIDISM PETER A. LEE, MICHAEL T. COUGHLIN, and MARK F. BELLINGER PETER A. LEEPETER A. LEE , MICHAEL T. COUGHLINMICHAEL T. COUGHLIN , and MARK F. BELLINGERMARK F. BELLINGER View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)66134-4AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We determined whether testicular size at orchiopexy is predictive of fertility potential and whether size correlates with sperm parameters, hormone levels or testicular volume in adulthood. Materials and Methods: Testicular size obtained from the operative notes of patients who underwent unilateral orchiopexy was classified as normal, small or large for age. These data were compared with outcome data. Paternity data were included on 166 men who reported achieving or unsuccessfully attempting paternity for 12 or more months. Of the men 49 provided blood for hormone level measurement, 43 underwent semen analysis and in 29 testicular volume was determined. Results: In the 166 men, including 98, 65 and 3 with small, normal and large testes for age at orchiopexy, respectively, there was no difference in paternity based on testicular size. Of those who achieved paternity time to conception did not differ based on size. Mean age at surgery also did not differ, nor did the percent of small versus normal testes in the age categories 0 to 2, 3 to 5, 6 to 8 and 9 to 11 years. There was no difference in men with small or normal testicular size at surgery in mean luteinizing hormone, follicle-stimulating hormone, testosterone or inhibin B. Sperm density, motility and morphology, and volume in adulthood of a previously undescended testis, previously descended testis or previously undescended and descended testes did not differ in these 2 groups, although the previously undescended testis was smaller than the contralateral testis. Conclusions: In men with a history of unilateral cryptorchidism small testicular size at orchiopexy is not associated with decreased paternity (89.8%), abnormal hormone levels, a lower sperm count or decreased testicular volume in adulthood. References 1 : Significance of testicular size measurement in andrology: II. Correlation of testicular size with testicular function. J Urol1987; 137: 416. Link, Google Scholar 2 : Ultrasonic texture and volume of testicles in infertile men. Hum Reprod1994; 9: 878. Google Scholar 3 : Unilateral testicular hypertrophy: an apparently benign occurrence without cryptorchidism. J Urol1982; 127: 329. 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Google Scholar 19 : Testicular volumes of adolescents. J Pediatr1982; 101: 1010. α. Google Scholar From the Department of Pediatrics, Penn State College of Medicine, Milton S. Hershey Medical Center, Hershey and Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh and Division of Pediatric Urology, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania© 2001 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byKalfa N (2020) Will He be Able to Give Me Grandchildren? Uncertainties about the Role of Hormones in Undescended TestisJournal of Urology, VOL. 203, NO. 4, (672-673), Online publication date: 1-Apr-2020.van der Plas E, Zijp G, Froeling F, van der Voort-Doedens L, Meij-de Vries A, Goede J and Hack W (2013) Long-Term Testicular Volume After Orchiopexy at Diagnosis of Acquired Undescended TestisJournal of Urology, VOL. 190, NO. 1, (257-262), Online publication date: 1-Jul-2013.Kraft K, Bhargava N, Schast A, Canning D and Kolon T (2011) Histological Examination of Solitary Contralateral Descended Testis in Congenital Absence of TestisJournal of Urology, VOL. 187, NO. 2, (676-681), Online publication date: 1-Feb-2012.Eijsbouts S, de Muinck Keizer-Schrama S and Hazebroek F (2007) Further Evidence for Spontaneous Descent of Acquired Undescended TestesJournal of Urology, VOL. 178, NO. 4S, (1726-1729), Online publication date: 1-Oct-2007.Lee P and Coughlin M (2018) The Single Testis: Paternity After Presentation as Unilateral CryptorchidismJournal of Urology, VOL. 168, NO. 4 Part 2, (1680-1683), Online publication date: 1-Oct-2002. Volume 166Issue 1July 2001Page: 236-239 Advertisement Copyright & Permissions© 2001 by American Urological Association, Inc.KeywordstestiscryptorchidismfertilityhormonespaternityMetrics Author Information PETER A. LEE More articles by this author MICHAEL T. COUGHLIN More articles by this author MARK F. BELLINGER More articles by this author Expand All Advertisement PDF downloadLoading ...