Catalytic Enantioselective 1,2‐Diboration of 1,3‐Dienes: Versatile Reagents for Stereoselective Allylation
2011; Wiley; Volume: 51; Issue: 2 Linguagem: Inglês
10.1002/anie.201105716
ISSN1521-3773
AutoresLaura T. Kliman, Scott N. Mlynarski, Grace E. Ferris, James P. Morken,
Tópico(s)Chemical Synthesis and Analysis
ResumoMore with boron: The development of catalytic enantioselective 1,2-diboration of 1,3-dienes enables a new strategy for enantioselective carbonyl allylation reactions (see scheme). These reactions occur with outstanding levels of stereoselection and can be applied to both monosubstituted and 1,1-disubstituted dienes. The carbonyl allylation reactions provide enantiomerically enriched functionalized homoallylic alcohol products.
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