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Identifying seizure clusters in patients with epilepsy

2005; Lippincott Williams & Wilkins; Volume: 65; Issue: 8 Linguagem: Inglês

10.1212/01.wnl.0000180685.84547.7f

1526-632X

Sheryl R. Haut, Richard B. Lipton, Aaron LeValley, Charles B. Hall, S. Shinnar,

Pharmacological Effects and Toxicity Studies

Clinicians often encounter patients whose neurologic attacks appear to cluster. In a daily diary study, the authors explored whether clustering is a true phenomenon in epilepsy and can be identified in the clinical setting. Nearly half the subjects experienced at least one episode of three or more seizures in 24 hours; 20% also met a statistical clustering criterion. Utilizing the clinical definition of clustering should identify all seizure clusterers, and false positives can be determined with diary data.