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Comparison of the Human Immunodeficiency Virus (HIV) Type 1-Specific Immunoglobulin G Capture Enzyme-Linked Immunosorbent Assay and the Avidity Index Method for Identification of Recent HIV Infections

2007; American Society for Microbiology; Volume: 46; Issue: 1 Linguagem: Inglês

10.1128/jcm.01055-07

1098-660X

Stephan Loschen, Jörg Bätzing-Feigenbaum, Gabriele Poggensee, Christiane Cordes, B Hintsche, Michael Rausch, S Dupke, Silvia Gohlke-Micknis, Jana Rödig, Osamah Hamouda, Claudia Kücherer,

HIV/AIDS drug development and treatment

The sensitivity and specificity of the human immunodeficiency virus (HIV) type 1-specific immunoglobulin G capture enzyme-linked immunosorbent assay (BED-CEIA) were compared with those of the avidity index method to identify recent HIV infection using a panel of 148 samples (81 patients) representing durations of infection ranging from 0 to 222 weeks. The results from the two tests were similar (sensitivity of 80% versus 74% [P = 0.53]; specificity of 86% versus 82% [P = 0.67]).