Paranasal Sinus Mucormycosis: a Report of Two Cases
2001; Taylor & Francis; Volume: 121; Issue: 8 Linguagem: Inglês
10.1080/00016480127363
ISSN1651-2251
Autores Tópico(s)Inflammatory mediators and NSAID effects
ResumoMucormycosis of the nose and paranasal sinuses is a rare invasive fungal infection, which often has a very fulminant course and characteristic clinical findings. The patients are usually immunocompromised, with diabetic ketoacidosis being the commonest underlying disorder. In some immunocompetent patients, the disease is associated with local predisposing factors, such as chronic sinusitis. Although the prognosis has improved in recent decades, the disease can still be fatal. The underlying disease is an important determinant of prognosis and correction of the metabolic disorder, if present, is essential. Herein we report two cases: one of our patients was immunocompetent but had earlier suffered from polypous rhinosinusitis whereas the other had mild adult-type diabetes. Both patients were successfully treated with surgical debridement and amphotericin B.
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