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Epidemiology of Recurrences or Reinfections of Clostridium difficile -Associated Diarrhea

2000; American Society for Microbiology; Volume: 38; Issue: 6 Linguagem: Inglês

10.1128/jcm.38.6.2386-2388.2000

1098-660X

Frédéric Barbut, A Koup Richard, Kheira Hamadi, Valérie Chomette, Béatrice Burghoffer, Jean‐Claude Petit,

Viral gastroenteritis research and epidemiology

Approximately 15 to 35% of patients with a first episode of Clostridium difficile-associated diarrhea relapse within 2 months. Between 1994 and 1997, strains from 93 hospitalized patients with C. difficile recurrences were fingerprinted by using both serotyping and PCR-ribotyping. The results showed that 48.4% of clinical recurrences were, in fact, reinfections with a different strain of C. difficile. Rates of clinical recurrences could therefore be reduced by implementing strict isolation precautions.