The artifactual nature of lipid peroxides detected in extracts of human aorta
1965; Elsevier BV; Volume: 5; Issue: 3 Linguagem: Inglês
10.1016/s0368-1319(65)80046-1
ISSN2212-1056
AutoresF. Peter Woodford, C. Böttcher, K. Oette, E. H. Ahrens,
Tópico(s)Cholesterol and Lipid Metabolism
ResumoLipid peroxides have been determined in lipid extracts of human aortas of varying degrees of atherosclerosis. Values lower than 2 μequiv./g lipid were obtained and evidence is presented that these, and the much higher values obtained by earlier workers, are largely attributable to artifactual formation of the peroxides during preparation of the tissue. This does not exclude the possibility of the participation of lipid peroxides in the atherosclerotic process.
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