Artigo Acesso aberto Revisado por pares

Pathological femoral fractures due to osteomalacia associated with adefovir dipivoxil treatment for hepatitis B: a case report

2012; BioMed Central; Volume: 7; Issue: 1 Linguagem: Inglês

10.1186/1746-1596-7-108

ISSN

1746-1596

Autores

Motoyuki Tanaka, Takao Setoguchi, Yasuhiro Ishidou, Yoshiya Arishima, Masataka Hirotsu, Yoshinobu Saitoh, Shunsuke Nakamura, Hironori Kakoi, Satoshi Nagano, Masahiro Yokouchi, Junichi Kamizono, Setsuro Komiya,

Tópico(s)

Bone health and treatments

Resumo

Abstract We present a case of a 62-year-old man who underwent total hip arthroplasty for treatment of pathologic femoral neck fracture associated with adefovir dipivoxil-induced osteomalacia. He had a 13-month history of bone pain involving his shoulders, hips, and knee. He received adefovir dipivoxil for treatment of lamivudine-resistant hepatitis B virus infection for 5 years before the occurrence of femoral neck fracture. Orthopedic surgeons should be aware of osteomalacia and pathological hip fracture caused by drug-induced renal dysfunction, which results in Fanconi’s syndrome. Virtual slides The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1600344696739249

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