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BIBTEX RIS

The Role of Nucleation Inhibition in Optical Resolutions with Families of Resolving Agents

2002; Wiley; Volume: 41; Issue: 22 Linguagem: Inglês

10.1002/1521-3773(20021115)41

ISSN

1521-3773

Autores

José W. Nieuwenhuijzen, R. F. P. Grimbergen, C. Koopman, Richard M. Kellogg, Ton R. Vries, Kees Pouwer, Erik van Echten, Bernard Kaptein, Lumbertus A. Hulshof, Q.B. Broxterman,

Tópico(s)

Molecular spectroscopy and chirality

Resumo

Not double Dutch! The resolution of racemates with families of structurally related resolving agents (see examples depicted) is termed Dutch Resolution. Certain family members are regularly not incorporated; these turn out to be nucleation inhibitors. This leads to a simplified, two-component resolution procedure with a high chance of initial success.

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