Sendai virus‐specific T cell clones. II. Induction of interferon production by Sendai virus‐specific T helper cell clones
1982; Wiley; Volume: 12; Issue: 12 Linguagem: Inglês
10.1002/eji.1830121212
ISSN1521-4141
AutoresHildegund C.J. Ertl, Earl G. Brown, Robert W. Finberg,
Tópico(s)Immune Cell Function and Interaction
ResumoAbstract Interferon (IFN) was detected upon co‐culture of cloned Sendai virus (SV)‐specific T lymphocyte with SV‐presenting syngeneic stimulator cells. The antiviral activity was defined as IFN‐α, β. The T cell clones, upon contact with antigen‐presenting stimulator cells, stimulated adherent cells present in the stimulator cell population to secrete IFN. Induction of IFN production was independent from interleukin 2 production by the T cell clones.
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