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Werner syndrome cells are sensitive to DNA cross‐linking drugs

2001; Wiley; Volume: 15; Issue: 7 Linguagem: Inglês

10.1096/fj.00-0611fje

1530-6860

Martin Poot, Sue S. Yom, Susan H. Whang, Jackson T. Kato, Katherine A. Gollahon, Peter S. Rabinovitch,

Cell death mechanisms and regulation

SPECIFIC AIMSTo define the type of chromatin lesion(s) that require the Werner syndrome (WRN) helicase/exonuclease activity to prevent cytotoxicity and S phase prolongation/arrest, we exposed lymph...