Artigo Acesso aberto Revisado por pares

IL-18 Attenuates Experimental Choroidal Neovascularization as a Potential Therapy for Wet Age-Related Macular Degeneration

2014; American Association for the Advancement of Science; Volume: 6; Issue: 230 Linguagem: Inglês

10.1126/scitranslmed.3007616

ISSN

1946-6242

Autores

Sarah Doyle, Ema Ozaki, Kiva Brennan, Marian M. Humphries, Kelly Mulfaul, James Keaney, Paul F. Kenna, Arvydas Maminishkis, Anna‐Sophia Kiang, Sean P. Saunders, Emily Hams, Ed C. Lavelle, Clair M. Gardiner, Padraic G. Fallon, Peter Adamson, Peter Humphries, Matthew Campbell,

Tópico(s)

Ocular Diseases and Behçet’s Syndrome

Resumo

IL-18 prevents choroidal neovascularization, the hallmark pathology of wet AMD, and is not toxic to the retinal pigment epithelium.

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