Portal de Periódicos da CAPES

Neonatal Cyanosis

1984; American Medical Association; Volume: 138; Issue: 9 Linguagem: Inglês

10.1001/archpedi.1984.02140470078027

2374-3018

Steven M. Yabek,

Neuroscience of respiration and sleep

More than a decade ago, Lees 1 provided a rational and systematic approach for differentiating pulmonary from cardiac causes of neonatal cyanosis. One of the modalities discussed was the response of arterial oxygen partial pressure (Pao 2 ) to 100% oxygen inhalation. Despite the caution that the response to 100% oxygen inhalation may be deceptive, some authors have since implied (erroneously) that a Pao 2 greater than 100 to 200 mm Hg 2,3 in response to 100% oxygen breathing rules out cyanotic congenital heart disease. This article was written to clarify persistent misconceptions regarding the response to hyperoxia and to explain the mechanisms of response to 100% oxygen breathing by infants with cyanotic heart disease. BASIC CONCEPTS AND DEFINITIONS Oxygen Transport What follows is a brief discussion of the concepts of oxygen transport and the relationships between the various laboratory tests for measuring and expressing the oxygen concentration in blood. 4 Arterial oxygen