Produção Nacional
Development and characterization of hydrogels based on natural polysaccharides: Policaju and chitosan
2014; Elsevier BV; Volume: 42; Linguagem: Inglês
10.1016/j.msec.2014.05.009
ISSN1873-0191
AutoresPaulo Rodinei Soares Lopes, Ana I. Bourbon, A. A. Vicente, César A.S. Andrade, Wilson Barros, Maria Tereza dos Santos Correia, Adalberto Pessoa, Maria G. Carneiro‐da‐Cunha,
Tópico(s)Polysaccharides Composition and Applications
ResumoThe development of hydrogels based on natural polysaccharides was investigated by preparing mixtures of policaju/chitosan at weight ratios of 1:4 and 2:3. Utilizing dynamic light scattering (DLS) techniques for these mixtures, an increase on the hydrodynamic particle radius was observed varying their pH from 3.0 to 12.0. Furthermore, a reduction of ζ-potential was also observed for the same pH interval. Following rounds of drying/hydration cycles at a specific pH value, hydrogel matrices were formed. The pore size distribution of these formed hydrogels was examined using scanning electron microscopy. Further FT-IR analyses confirmed a physical interaction between the polysaccharides policaju and chitosan. Swelling experiments revealed water uptake values, after 24 h of immersion in water, close to 270% for 1:4, and 320% for 2:3 hydrogels. Finally, rheological measurements were then conducted in order to confirm hydrogel viscoelastic features. These results indicate a promising road to biomaterials fabrication and biomedical applications.
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