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Estimation of left ventricular filling pressures by speckle tracking echocardiography in patients with idiopathic dilated cardiomyopathy

2010; Oxford University Press; Volume: 12; Issue: 1 Linguagem: Inglês

10.1093/ejechocard/jeq088

1525-2167

Jaroslav Meluzı́n, Lenka Špinarová, P Hude, Jan Krejčí, Helena Podroužková, Martin Pešl, Marek Orban, Ladislav Dušek, Jiří Jarkovský, Josef Kořínek,

Cardiac Imaging and Diagnostics

The ratio of early diastolic transmitral flow velocity (E) to early diastolic mitral annular velocity (Ea) is frequently used to predict an increase in left ventricular filling pressure (LVFP). However, this approach has several limitations. The aim of this study was to test whether additional information is gained by new echocardiographic indexes utilizing strain and strain rate (SR) derived from 2-dimensional speckle tracking echocardiography (2D-STE) for the estimation of LVFP. Fifty-one patients with idiopathic dilated cardiomyopathy (IDC) underwent pulsed-wave tissue Doppler echocardiography and 2D-STE performed simultaneously with right heart catheterization. Receiver operating characteristic analysis showed that circumferential strain and the SR during late diastolic LV filling (0.956 and 0.951, both P = 0.001), E/circumferential SR at early diastolic LV filling (0.949, P = 0.001), and E/circumferential strain at the time of peak E-wave (0.948, P = 0.001) had greater area under the curve than the E/Ea ratio (0.911, P = 0.001) for the prediction of pulmonary capillary wedge pressure > 12 mmHg. When compared with the E/Ea ratio, several 2D-STE-derived parameters better estimated the increase in LVFP in patients with IDC.