Produção Nacional
Revisado por pares
Allele frequencies of the five new generation forensic STR (D1S1656, D2S441, D10S1248, D12S391 and D22S1045) in the population from Rio Grande do Sul, Southern Brazil
2011; Elsevier BV; Volume: 6; Issue: 1 Linguagem: Inglês
10.1016/j.fsigen.2011.04.016
ISSN1878-0326
AutoresRodrigo Rodenbusch, Simone Schumacher, Ana Carolina Mardini, Fernanda Goulart Lanes Chula, Candice Tosi Michelon, Candice Tosi Michelon, André Zoratto Gastaldo, Lila Particheli Maciel, Gabriela C.R. Hirschfeld-Campolongo, Paulo Eduardo Raimann, Sabrina Esteves de Matos Almeida, Cláudia Maria Dornelles da Silva,
Tópico(s)Genetic diversity and population structure
ResumoAllele frequencies of the five recently introduced European Standard Set (ESS) [ [1] Gill P. Fereday L. Morling N. Schneider P.M. The evolution of DNA databases – recommendations for new European STR. Forensic Sci. Int. 2006; 156: 242-244 Abstract Full Text Full Text PDF PubMed Scopus (192) Google Scholar ] STRs markers (D1S1656, D2S441, D10S1248, D12S391 and D22S1045) [ 2 Lareu M.V. Pestoni C. Schürenkamp M. Rand S. Brinkmann B. Carracedo A. A highly variable STR at the D12S391 locus. Int. J. Leg. Med. 1996; 109: 134-138 Crossref PubMed Scopus (79) Google Scholar , 3 Lareu M.V. Barral S. Salas A. Pestoni C. Carracedo A. Sequence variation of a hypervariable short tandem repeat at the D1S1656 locus. Int. J. Leg. Med. 1998; 111: 244-247 Crossref PubMed Scopus (56) Google Scholar ] were obtained from a sample of 353 individuals undergoing paternity testing in the population of Rio Grande do Sul, Southern Brazil. Rio Grande do Sul was essentially colonized by Portuguese, Germans, and Italians immigrants in the 18th century [ [4] Instituto Brasileiro de Geografia Estatística (IBGE), Brasil 500 anos de povoamento, IBGE, Rio de Janeiro, 2000. Google Scholar ]. All participants signed informed consent forms (Table 1). Table 1Allele frequencies of the new five STR loci, HWE and parameters of forensic interest estimated for Rio Grande do Sul population, Southern Brazil. Allele D1S1656 D2S441 D10S1248 D12S391 D22S1045 9 0.0014 10 0.0042 0.2904 0.0014 0.0128 11 0.0453 0.2720 0.0071 0.1006 11.3 0.0453 12 0.1006 0.0467 0.0439 0.0071 12.3 0.0014 13 0.0737 0.0269 0.2691 0.0042 13.3 0.0014 14 0.1190 0.2720 0.3215 0.0467 14.3 0.0113 15 0.1671 0.0368 0.2025 0.0368 0.3640 15.3 0.0425 16 0.1360 0.0057 0.1261 0.0297 0.3782 16.3 0.0609 17 0.0382 0.0241 0.1006 0.0822 17.3 0.1346 0.0227 18 0.0057 0.0042 0.1997 0.0042 18.3 0.0581 0.0255 19 0.1601 19.1 0.0028 19.3 0.0028 0.0099 20 0.1416 20.3 0.0028 21 0.0822 22 0.0623 23 0.0751 24 0.0340 25 0.0085 26 0.0028 27 0.0028 N 706 706 706 706 706 HO 0.898 0.771 0.751 0.884 0.711 HE 0.894 0.762 0.766 0.885 0.706 PIC 0.884 0.723 0.727 0.873 0.656 PD 0.976 0.896 0.910 0.972 0.865 PE 0.818 0.542 0.511 0.763 0.446 P 0.975 0.022 * P: not statistically significant after Bonferroni's correction. 0.808 0.757 0.399 N: number of chromosomes; Ho: observed heterozygosity; He: expected heterozygosity; PIC: polymorphism information content; PD: power of discrimination; PE: power of exclusion; P: Hardy-Weinberg equilibrium exact probability tests. * P: not statistically significant after Bonferroni's correction. Open table in a new tab N: number of chromosomes; Ho: observed heterozygosity; He: expected heterozygosity; PIC: polymorphism information content; PD: power of discrimination; PE: power of exclusion; P: Hardy-Weinberg equilibrium exact probability tests.
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