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Intravenous amiodarone in intensive care

2000; Springer Science+Business Media; Volume: 26; Issue: 12 Linguagem: Inglês

10.1007/s001340000668

1432-1238

Martin Hughes, A. Binning,

ECG Monitoring and Analysis

Amiodarone is widely used in intensive care units for the treatment of a variety of arrhythmias. It is currently the drug of choice for supraventricular tachyarrhythmias in many units because of its combination of efficacy and safety. This review summarises the current state of knowledge regarding the short-term administration of intravenous amiodarone to control arrhythmias in perioperative, coronary care and intensive care patients. It outlines the electrophysiology, haemodynamics, pharmacokinetics and toxicity of the drug. In particular, it examines the recent concerns regarding acute pulmonary toxicity.