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Construction of Nitrogen‐Containing Heterocycles by CH Bond Functionalization

2009; Wiley; Volume: 15; Issue: 24 Linguagem: Inglês

10.1002/chem.200900281

1521-3765

Praew Thansandote, Mark Lautens,

Cyclopropane Reaction Mechanisms

Nitrogen heterocycles are abundant in natural products and pharmaceuticals. An emerging interest among synthetic chemists is to use C-H functionalization to construct the nitrogen-containing core of these heterocycles. The following article will provide a brief overview of this concept with respect to the type of C-H bond functionalized.