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Intravaginal Practices, Vaginal Flora Disturbances, and Acquisition of Sexually Transmitted Diseases in Zimbabwean Women

2000; Oxford University Press; Volume: 181; Issue: 2 Linguagem: Inglês

10.1086/315227

1537-6613

Janneke van de Wijgert, P. R. Mason, Lovemore Gwanzura, Michael T. Mbizvo, Zvavahera M. Chirenje, Virginia Iliff, Stephen Shiboski, Nancy Padian,

Syphilis Diagnosis and Treatment

One hundred sixty-nine Zimbabwean women were studied to determine whether the use of intravaginal practices (cleaning with the fingers, wiping the vagina, and inserting traditional substances) are associated with disturbances of vaginal flora and acquisition of sexually transmitted diseases (STDs). Subjects were interviewed and received counseling and a pelvic examination at enrollment, 1 month, and 6 months, and vaginal specimens were collected at enrollment and at 6 months. Users were more likely than nonusers to have vaginal flora disturbances but were not more likely to acquire an STD (relative risk [RR], 2.15; P = .188). Certain vaginal flora disturbances were associated with increased STD incidence and HIV prevalence. The absence of lactobacilli from the vaginal flora was associated with being positive for human immunodeficiency virus in baseline (odds ratio [OR], 0.24; P = .001) and 6-month transition multivariate models (OR, 0.39; P = .025). The presence of clue cells at baseline was associated with a higher incidence of STDs (RR, 1.94; P = .025).