Relation of Serum and Erythrocyte Magnesium Levels to Blood Pressure and a Family History of Hypertension A Follow-up Study in Japanese Children, 12-14 Years Old
1990; Wiley; Volume: 79; Issue: 3 Linguagem: Inglês
10.1111/j.1651-2227.1990.tb11463.x
ISSN1651-2227
AutoresY Shibutani, Kunihiro Sakamoto, Shingo Katsuno, Shusuke Yoshimoto, Takamaro Matsuura,
Tópico(s)Magnesium in Health and Disease
ResumoSerum and erythrocyte magnesium concentrations (S-Mg, E-Mg) were measured in 122 junior high school students followed up for two years from 12 to 14 years of age, and the relationship to blood pressure and a family history of hypertension were investigated. The subjects who had high S-Mg and E-Mg levels at the first examination two years prior tended to show high levels after this follow-up. There were significant positive correlations between two intraindividual values of S-Mg and E-Mg. A similar tendency was found for blood pressure. Tracking phenomena were observed with these measures. The subjects who had high E-Mg levels at the first examination showed no blood pressure elevation during the two-year period. The subjects with a family history of hypertension [FH(+)] showed a higher degree of blood pressure rise during two years than those with no family history [FH(-)], with a significant difference in systolic blood pressure at the age of 14. E-Mg tended to be lower in the FH(+) group than in the FH(-) group with a significant difference in 14-year-old girls. These results suggest that a hereditary predisposition to hypertension is related to magnesium metabolism and that intracellular magnesium deficiency may influence blood pressure elevation in the FH(+) children.
Referência(s)