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BIBTEX RIS

Two Independent Apolipoprotein A5 Haplotypes Modulate Postprandial Lipoprotein Metabolism in a Healthy Caucasian Population

2007; Oxford University Press; Volume: 92; Issue: 6 Linguagem: Inglês

10.1210/jc.2006-1802

ISSN

1945-7197

Autores

Rafael Moreno‐Luna, Francisco Pérez‐Jiménez, Carmen Marı́n, Pablo Pérez‐Martínez, Purificación Gómez, Yolanda Jiménez, Javier Delgado‐Lista, Juan Antonio Moreno, Toshiko Tanaka, José M. Ordovás, José López‐Miranda,

Tópico(s)

Lipid metabolism and biosynthesis

Resumo

Background: Apolipoprotein A5 (APOA5) plays an important role in plasma triacylglycerol (TG) homeostasis. Five polymorphisms (1131T>C, c.-3A>G, c.56C>G, IVS3+476G>A, and c.1259T>C) in the APOA5 gene define three common haplotypes (APOA5*1, APOA5*2, and APOA5*3) in Caucasian individuals. Our aim was to determine whether these haplotypes could modulate the postprandial response in young healthy males.

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