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L-Carnitine Administration to Hemodialysis Patients: Has Its Time Come?

1992; Wiley; Volume: 5; Issue: 2 Linguagem: Inglês

10.1111/j.1525-139x.1992.tb00119.x

1525-139X

Thomas A. Golper, Suhail Ahmad,

Epilepsy research and treatment

Seminars in DialysisVolume 5, Issue 2 p. 94-98 L-Carnitine Administration to Hemodialysis Patients: Has Its Time Come? Thomas A. Golper, Corresponding Author Thomas A. Golper Departments of Medicine, University of Louisville, Louisville, Kentucky (TAG) and University of Washington, Seattle, Washington (SA)Thomas A. Golper, MD, Professor of Medicine, Kidney Disease Program, 500 South Floyd Street, University of Louisville, Louisville, KY 40292.Search for more papers by this authorSuhail Ahmad, Suhail Ahmad Departments of Medicine, University of Louisville, Louisville, Kentucky (TAG) and University of Washington, Seattle, Washington (SA)Search for more papers by this author Thomas A. Golper, Corresponding Author Thomas A. Golper Departments of Medicine, University of Louisville, Louisville, Kentucky (TAG) and University of Washington, Seattle, Washington (SA)Thomas A. Golper, MD, Professor of Medicine, Kidney Disease Program, 500 South Floyd Street, University of Louisville, Louisville, KY 40292.Search for more papers by this authorSuhail Ahmad, Suhail Ahmad Departments of Medicine, University of Louisville, Louisville, Kentucky (TAG) and University of Washington, Seattle, Washington (SA)Search for more papers by this author First published: April 1992 https://doi.org/10.1111/j.1525-139X.1992.tb00119.xCitations: 18AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 Bahl JJ, Bressler R: The pharmacology of carnitine. 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Kidney Int 36(Suppl 27): 259– 263, 1989. 40 Ahmad S, Robertson HT, Golper TA, Wolfson, Kurtin P, Katz LA, Hirschberg R, Nicora R, Ashbrook DW, Kopple JD: Multicenter trial of L-carnitine in maintenance hemodialysis patients. II. Clinical and biochemical effects. Kidney Int 38: 912– 918, 1990. 41 Giorcelli G, Corsi M: Nutritional patterns of response to L-carnitine in patients on chronic hemodialysis (abstract). Kidney Int 24(Suppl 16): 328, 1983. 42 Casciani CV, Caruso U: Beneficial effects of L-carnitine in post-dialysis syndrome. Curr Ther Res 32: 116– 127, 1982. 43 Suzuki Y, Narita M, Yamazaki N: Effects of L-carnitine on arrhythmias during hemodialysis. Jpn Heart J 23: 349– 358, 1982. 44 Giordani MP, Corsi M, Roncarolo P, Falcone M, Gabasio C: Effect of L-carnitine on systolic time intervals in coronary artery disease. Curr Ther Res 33: 305– 311, 1983. 45 Garzya G, Amico RM: Comparative study on the activity of racemic and levorotatory carnitine in stable angina pectoris. 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Lancet 2: 1028, 1980. 55 Brunzell JD, Albers JJ, Haas LB, Goldberg AP, Agadoa L, Sherrard DJ: Prevalence of serum lipid abnormalities in chronic hemodialysis. Metabolism 26: 903– 910, 1977. 56 Fagher B, Cederblad G, Eriksson M, Monti M, Moritz U, Nilsson-Ehle P, Thysell H: L-Carnitine and haemodialysis: Double-blind study on muscle function and metabolism and peripheral nerve function. Scand J Clin Lab Invest 45: 169– 178, 1985. 57 Spagnoli LG, Palmieri G, Mauriello A, Vacha GM, D'Iddio S, Giorcelli G, Corsi M: Morphometric evidence of the trophic effect of L-carnitine on human skeletal muscle. Nephron 55: 16– 23, 1990. 58 Borah MF, Schoenfeld PY, Gotch FA, Sargent JA: Nitrogen balance during intermittent dialysis therapy of uremia. Kidney Int 14: 491– 500, 1978. 59 Bergstrom J: Hemodialysis–Does the membrane matter? (editorial). Semin Dial 2: 7– 10, 1989. 60 Hallgren R, Karlsson FA, Roxin LE, Vange P: Myoglobin turnover–Influence of renal function. 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Proc Eur Dial Transplant Assoc 19: 302– 307, 1982. 65 Trovato GM, Ginardi V, Di Marco V, Dell'Aira AE, Corsi M: Long-term L-carnitine treatment of chronic anaemia of patients with end-stage renal failure. Curr Ther Res 31: 1042– 1049, 1982. 66 Labonia WD, Morelli OH, Gimenez MI, Freuler PV, Morelli OH: Effects of L-carnitine on sodium transport in erythrocytes from dialyzed uremic patients. Kidney Int 32: 754– 759, 1987. 67 Farrell S, Vogel J, Bieber LL: Entry of acetyl-L-carnitine into biosyn-thetic pathways. Biochim Biophys Acta 876: 175– 177, 1986. 68 Donatelli A, Terrizzi C, Zummo G, Russo V, Bucalo ML, Scarpinato A: Effects of L-carnitine on chronic anemia and erythrocyte adenosine triphosphate concentration in hemodialyzed patients. Curr Ther Res 41: 620– 624, 1987. 69 Yderstraede KB, Pedersen FB, Dragsholt C, Trostmann A, Laier E, Larsen HF: The effect of L-carnitine on lipid metabolism in patients on chronic haemodialysis. Nephrol Dial Transplant 1: 238– 241, 1987. 70 Vacha GM, Giorcelli G, D'Iddio S, Valentini G, Bagiella E, Procopio A, di Donato S, Ashbrook D, Corsi M: L-Carnitine addition to dialysis fluid: A therapeutic alternative for hemodialysis patients. Nephron 51: 237– 242, 1989. Citing Literature Volume5, Issue2April 1992Pages 94-98 ReferencesRelatedInformation