Artigo Revisado por pares

The Sharpless Asymmetric Aminohydroxylation -Scope and Limitation

2002; Wiley; Volume: 344; Issue: 10 Linguagem: Inglês

10.1002/1615-4169(200212)344

ISSN

1615-4169

Autores

D. B. Nilov, Oliver Reiser,

Tópico(s)

Chemical Synthesis and Analysis

Resumo

The asymmetric aminohydroxylation (AA) has emerged as a valuable tool in organic synthesis. Recent developments, such as ligandless variants, new nitrogen reagents and new substrates have considerably broadened the utility of the process. Nevertheless, the understanding of the AA, both in terms of mechanism as well as applicability to common synthetic tasks is still limited. This article summarizes the scope and limitation of the AA with special emphasis on recent advances.

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