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Medical comorbidity in recurrent versus first-episode depressive patients

2010; Wiley; Volume: 123; Issue: 3 Linguagem: Inglês

10.1111/j.1600-0447.2010.01646.x

1600-0447

Margalida Gili, Mauro García‐Toro, Margalida Vives Barceló, S. Armengol, Javier García‐Campayo, Joan B. Soriano, Miquel Roca,

Treatment of Major Depression

Acta Psychiatrica ScandinavicaVolume 123, Issue 3 p. 220-227 Medical comorbidity in recurrent versus first-episode depressive patients M. Gili, M. Gili Institut Universitari d’Investigació en Ciències de la Salut (IUNICS), University of Balearic Islands, Palma de Mallorca Red de Actividades Preventivas y Promoción de la Salud en Atención Primaria (RediAPP), BarcelonaSearch for more papers by this authorM. Garcia-Toro, M. Garcia-Toro Institut Universitari d’Investigació en Ciències de la Salut (IUNICS), University of Balearic Islands, Palma de Mallorca Red de Actividades Preventivas y Promoción de la Salud en Atención Primaria (RediAPP), BarcelonaSearch for more papers by this authorM. Vives, M. Vives Institut Universitari d’Investigació en Ciències de la Salut (IUNICS), University of Balearic Islands, Palma de Mallorca Red de Actividades Preventivas y Promoción de la Salud en Atención Primaria (RediAPP), BarcelonaSearch for more papers by this authorS. Armengol, S. Armengol Almirall Medical Department, Almirall Spain, BarcelonaSearch for more papers by this authorJ. Garcia-Campayo, J. Garcia-Campayo Red de Actividades Preventivas y Promoción de la Salud en Atención Primaria (RediAPP), Barcelona Department of Psychiatry, Miguel Servet Hospital, University of Zaragoza, ZaragozaSearch for more papers by this authorJ. B. Soriano, J. B. Soriano Program of Epidemiology & Clinical Research, Fundació Caubet-CIMERA, Bunyola, SpainSearch for more papers by this authorM. Roca, M. Roca Institut Universitari d’Investigació en Ciències de la Salut (IUNICS), University of Balearic Islands, Palma de Mallorca Red de Actividades Preventivas y Promoción de la Salud en Atención Primaria (RediAPP), BarcelonaSearch for more papers by this author M. Gili, M. Gili Institut Universitari d’Investigació en Ciències de la Salut (IUNICS), University of Balearic Islands, Palma de Mallorca Red de Actividades Preventivas y Promoción de la Salud en Atención Primaria (RediAPP), BarcelonaSearch for more papers by this authorM. Garcia-Toro, M. Garcia-Toro Institut Universitari d’Investigació en Ciències de la Salut (IUNICS), University of Balearic Islands, Palma de Mallorca Red de Actividades Preventivas y Promoción de la Salud en Atención Primaria (RediAPP), BarcelonaSearch for more papers by this authorM. Vives, M. Vives Institut Universitari d’Investigació en Ciències de la Salut (IUNICS), University of Balearic Islands, Palma de Mallorca Red de Actividades Preventivas y Promoción de la Salud en Atención Primaria (RediAPP), BarcelonaSearch for more papers by this authorS. Armengol, S. Armengol Almirall Medical Department, Almirall Spain, BarcelonaSearch for more papers by this authorJ. Garcia-Campayo, J. Garcia-Campayo Red de Actividades Preventivas y Promoción de la Salud en Atención Primaria (RediAPP), Barcelona Department of Psychiatry, Miguel Servet Hospital, University of Zaragoza, ZaragozaSearch for more papers by this authorJ. B. Soriano, J. B. Soriano Program of Epidemiology & Clinical Research, Fundació Caubet-CIMERA, Bunyola, SpainSearch for more papers by this authorM. Roca, M. Roca Institut Universitari d’Investigació en Ciències de la Salut (IUNICS), University of Balearic Islands, Palma de Mallorca Red de Actividades Preventivas y Promoción de la Salud en Atención Primaria (RediAPP), BarcelonaSearch for more papers by this author First published: 30 November 2010 https://doi.org/10.1111/j.1600-0447.2010.01646.xCitations: 24 M. Gili, Institut Universitari d’Investigació en Ciències de la Salut (IUNICS), University of Balearic Islands, Carretera de Valldemossa km 7.5, 07071 Palma de Mallorca, Spain.E-mail: mgili@uib.es Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Gili M, Garcia-Toro M, Vives M, Armengol S, Garcia-Campayo J, Soriano JB, Roca M. Medical comorbidity in recurrent versus first-episode depressive patients. Objective: This study compares the comorbidity of affective disorders and medical diseases in primary care patients with either a first or recurrent depressive episode. Method: A cross-sectional epidemiological study in primary care centres in Spain was designed. A total of 10 257 primary care patients suffering a DSM-IV major depressive episode (MDD) were analysed. Depression was assessed using the Montgomery–Asberg Depression Rating Scale (MADRS), and World Health Organization (WHO) medical diagnoses were provided by the patient’s general practitioner according to medical records revised on the basis of radiology or laboratory test data. Results: A total of 88.6% of recurrent patients and 71.1% of first-episode depressive patients reported a medical condition (aOR = 2.61, CI = 2.31–2.93). All medical conditions were more prevalent in the recurrent group than in first-episode group, and with the exception of myocardial infarction, psoriasis and migraine, all other crude ORs showed statistically significant differences between first- and recurrent episodes patients after adjusting for gender, age, education, socioeconomic status and body mass index (BMI). Conclusion: Recurrent depression is associated with a decrement in health that is significantly greater than in first-episode depression. Special attention needs to be paid to the physical health in the middle- and long-term management of patients with affective disorders. Citing Literature Volume123, Issue3March 2011Pages 220-227 RelatedInformation